Abstract

“We don't beat the Reaper by living longer. We beat the Reaper by living well.” Professor Randy Pausch declared this statement during his famous last lecture at Carnagie Mellon University prior to his death from pancreatic cancer in 2008 [1]. As opposed to the widely practiced WHO approach of utilizing opioids in a stepladder fashion, many now advocate a mechanism-based approach to cancer pain treatment. Old dogma treated cancer pain as a problem mainly toward the end of life situation in the context of metastatic, progressive disease, whereas new data show pain to be problematic throughout the cancer care cycle [2]. The effective management of these acutely painful surgeries and related treatments may limit the development of chronic pain states in long-term survivors [3]. Effective treatment strategies include multidisciplinary, multimodal care utilizing 1) combinations of long-acting opioids for constant pain with short-acting opioids for incidental pain; 2) “adjuvant” co-analgesics including nonsteroidal anti-inflammatories, anticonvulsants, antidepressants, and topical agents to optimize analgesia and minimize opioid doses, thereby reducing concomitant opioid-related side effects; 3) prophylactic treatment of constipation, nausea, and other common troublesome symptoms; 4) interventional …

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.