Palladium-Catalyzed Synthesis of Aryl Ketones from Boronic Acids and Carboxylic Acids or Anhydrides We thank M. Rössig and L. Winkel for technical assistance, Prof. Dr. M. T. Reetz for generous support and constant encouragement, and the DFG for financial support.

Abstract

Mild and convenient: a palladium-catalyzed cross-coupling reaction between arylboronic acids and carboxylic anhydrides, which are generated in situ from the corresponding carboxylic acids, allows the efficient synthesis of a broad variety of functionalized aryl ketones [Eq. (1)].