Palladium‐Catalyzed Ring‐Expansion Reaction of Indoles with Alkynes: From Indoles to Tetrahydroquinoline Derivatives Under Mild Reaction Conditions

Abstract

A cut and shut job: The highly selective title reaction proceeds, using O2 as the oxidant, to afford tetrahydroquinoline derivatives. This chemistry offers a new approach to polysubstituted 4,5-dihydrocyclopenta[c]quinolines, and also valuable mechanistic insight into this ring-expansion reaction. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.