Abstract
A simple and ligand-free protocol has been developed for the Pd(OAc)2-catalyzed Suzuki reaction of potassium aryltrifluoroborates in aqueous ethanol under air. In the presence of Pd(OAc)2 and 1 equiv. of K2CO3, aryl or heteroaryl halides coupled with various potassium aryltrifluoroborates smoothly to afford the products in high yields with the highest turnover frequency (TOF) up to 4656 h -1 , and a series of triphenylamine derivatives were prepared efficiently in this system. In addi- tion, the active catalyst was proved to be the in situ-generated palladium nanoparticles according to TEM analysis and mercu- ry-poisoning test. Keywords palladium; ligand-free; Suzuki reaction; potassium aryltrifluoroborates; aqueous ethanol
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