Palladium-Catalysed Carbonylative Cross-Coupling Reactions of Aryl Iodides and Vinyl Boron Derivatives as a Straightforward Route to Aryl Vinyl Ketones

Abstract

The carbonylative cross-coupling of potassium vinyl trifluoroborate or 2,4,6-trivinyltricycloboroxane with aryl iodides under mild conditions affords aryl vinyl ketones. The optimisation of the reaction conditions leads to the targeted enones in good yields in the case of the aryl substrates bearing donor substituents in meta or para position. Much more moderate yields were observed with aryl substrates bearing withdrawing substituents.