Abstract
A new ligand of serotoninergic receptors was synthesized by cross coupling between a triamine and an arylimidoyl chloride. A comparison of the different methods used to make a ‘pseudo-amidinic’ bond from primary amines and an imidoyl chloride is presented. The best results were obtained using Pd 2dba 3:BINAP catalysis (0.25:0.75%, respectively).
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