Abstract
A convenient and efficient approach for the synthesis of 4-heteroaryl quinolinones was developed via palladium/copper-catalyzed coupling reactions between 4-quinolinonyl triflates with benzothiazole/benzoxazole/thiazole/oxazole/benzimidazole. Biological evaluation revealed that some of the obtained products exhibited in vitro antiproliferative activities on human-derived live cancer cell lines.
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