Abstract

Palladium-catalyzed Wacker-type oxidation of N -Boc indoles for the synthesis of 3-oxyindolines has been developed. The palladium-catalyzed Wacker-type oxidation of N -Boc indoles can readily occur in MeCN using H 2 O 2 as oxidant. And 3-oxyindolines were obtained in medium to high yield. Furtherly, the mechanism of palladium-catalyzed Wacker-type oxidation of N -Boc indoles was proposed.

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