Abstract
AbstractCarboxylic acids are an abundant and structurally diverse class of commercially available materials, which are commonly used as stable reagents in organic synthesis. The Suzuki–Miyaura coupling reaction directly using carboxylic acid as a substrate has been rarely reported. Here, we report an efficient coupling reaction of carboxylic acids with arylboronic acids in toluene in the presence of IPrCl-Cl, Pd(OAc)2, PPh3, and K3PO4·7H2O at 90 °C to give the corresponding aryl ketones.
Published Version
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