Abstract
Palladium‐catalyzed remote meta‐selective C‐H functionalization of arylacetic acid has been developed using a pyrimidine template. This transformation is not only tolerated to a diverse range of arylacetic acid and alkene substrates but also applicable to the synthesis of pharmaceutically active ibuprofen derivatives. Moreover, the pyrimidine template was readily removable and recyclable under mild conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.