Abstract
AbstractThe diastereoselective synthesis of anti‐homoallylic alcohols bearing conjugated (Z)‐enynes through a palladium‐catalyzed three‐component reaction is described. This reaction features a broad substrate scope, good functional group compatibility, and high levels of (Z)‐alkene stereocontrol. In this reaction, Pd(0) functions as a catalyst in two fundamental steps of the tandem sequence: 1) the generation of a borylated π‐allylpalladium species from bifunctional conjunctive reagents, inducing umpolung allylation of aldehydes, and 2) C(sp2)−C(sp) cross‐coupling. Further transformations of the obtained products highlight their synthetic utility.magnified image
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
