Abstract
AbstractA combination of palladium and silane has been well used for the catalytic desulfurative cross‐coupling reactions under neutral conditions. Catalyzed by 10 mol‐% of bis(triphenylphosphine) palladium(II) dichloride in dimethylformamide in the presence of 2 equiv. of triphenylsilane, the carbocyclizations of α‐(3‐butenoyl) ketene dithioacetals took place smoothly leading to 2‐cyclopentenones in high yields. Thus, a new Heck‐type cyclization based on C–S bond cleavage for the synthesis of spiro compounds by using silanes as the desulfurative agents has been established.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.