Abstract
AbstractA palladium‐catalyzed cascade carbonylative/cyclization reaction for the synthesis of 2‐(trifluoromethyl)quinazolin‐4(3H)‐ones has been achieved. The transformation utilizes readily available 2‐iodoanilines and trifluoroacetimidoyl chlorides as the starting reagents, enabling a simple and convenient access to pharmaceutically significant quinazolin‐4(3H)‐one derivatives.
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