Abstract

A method for the construction of various thio-bridged compounds is developed using readily available o-(trimethylsilyl)aryl triflates as a source of aryne precursor, catalyzed by simple Pd(dba)2/dppe complex. This operationally simple and modular protocol allows thio-bridged compound via C(sp2)-C(sp2) and C(sp2)-C(sp3) bond formation in promising yields with a broad substrate scope. The key part is in situ generation of an aryne from o-(trimethylsilyl)aryl triflates and their subsequent intermolecular annulation.

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