Abstract

The potential for palatine shelf fusion in cortisone-treated mouse fetuses was tested by mechanically displacing the tongue from between the shelves. Fusion occurred in 51 per cent of 135 fetuses so treated, compared to 19 per cent of 117 fetuses released from the uterus without tongue displacement. Thus, the ability of a substantial number of palatine shelves to fuse after cortisone treatment, as originally demonstrated by tongue excision, was confirmed by a less traumatic technique.

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