Abstract
Shah Murad*1, Hafiz Moeen Ud Din2, Farid Ud Din3, Abdul Ghaffar4, Seema Shah Murad5, Jamila Shah6 and Manal Rauf Mahar7 Author Affiliations 1Professor of Pharmacology, Pakistan 2Associate Prof of Anatomy at AIMC Lahore Pakistan, Pakistan 3Lecturer Pharmacology at DANTH Islamabad Pakistan, Pakistan 4CWO at IMDC and DANTH, Pakistan 5Gynecologist at NMC Karachi Pakistan, Pakistan 6Psychologist at BU Karachi Pakistan, Pakistan 7Dentist at IDH, Pakistan Received: December 17, 2019 | Published: January 06, 2020 Corresponding author: Shah Murad, Professor of Pharmacology, IMDC, Islamabad, Pakistan DOI: 10.26717/BJSTR.2020.24.004030
Highlights
Metabolic syndrome is associated with hyperglycemia, hyperlipidemia, and hypertension [1]
In presence of high levels of blood LDL particles, free radicals (ROS), macrophages, cytokines, platelets, histamine, 5HT get involved in LDL oxidation, leading to formation of atherosclerotic plaques which get deposited in endothelium of coronary arteries causing coronary artery disease (CAD)
We concluded that Ficus Carica (FC) and Psyllium Husk (PH) have good enough potential to normalize lipid profile, reduce BP, and Fasting blood glucose (FBS) in patients suffering from metabolic syndrome
Summary
Metabolic syndrome is associated with hyperglycemia, hyperlipidemia, and hypertension [1]. Hypertension, and hyperlipidemia are directly related with oxidative stress in human body [2,3]. Increased LDL particles in blood interacts with reactive oxygen species (ROS) causing LDL-oxidation and leading to formation of atherosclerotic plaques which usually get deposited in endothelium of coronary arteries leading to develop CAD [4]. In presence of high glucose levels hyperlipidemia, and hypertension this atherosclerotic plaque formation process can be accelerated [5]. Preventable risk factors for these three metabolic aberrations include to stop over ingestion of junk foods, alcohol, carbohydrate/ fats, stop smoking, and escaping sedentary life [6]. If individual still get illness like this syndrome, he or she can start treating this metabolic syndrome by regular utilization of Psyllium Husk (PH)
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