Abstract

BackgroundThe diagnosis of deep vein thrombosis of leg is very common in clinical practice. Not infrequently a range of pathologies are diagnosed after excluding a thrombosis, often after a period of anticoagulation.Case presentationThis is a report of three patients who presented with a painful swollen leg and were initially treated as a deep vein thrombosis or a baker's cyst, but later diagnosed as a pleomorphic sarcoma, a malignant giant cell tumor of the muscle and a myxoid liposarcoma. A brief review of such similar reports and the relevant literature is presented.ConclusionA painful swollen leg is a common clinical scenario and though rare, tumors must be thought of without any delay, in a duplex negative, low risk deep vein thrombosis situation.

Highlights

  • The diagnosis of deep vein thrombosis of leg is very common in clinical practice

  • We report three case histories of patients managed initially as a Deep vein thrombosis (DVT) of calf or a baker's cyst and later referred to our centre with a provisional diagnosis of a soft tissue tumor

  • The D-dimers were normal and a Doppler scan ruled out a DVT, but a baker's cyst was diagnosed

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Summary

Background

Painful swollen leg is a common clinical scenario. Deep vein thrombosis (DVT) often presents as a painful swollen leg and prompt management is vital to prevent fatal pulmonary embolism. We report three case histories of patients managed initially as a DVT of calf or a baker's cyst and later referred to our centre with a provisional diagnosis of a soft tissue tumor. After 3 weeks of anticoagulation there was evidence of a lump in the left popliteal fossa and ultrasound scan of the area revealed a solid soft-tissue mass. The D-dimers were normal and a Doppler scan ruled out a DVT, but a baker's cyst was diagnosed Following this episode the symptoms never settled and he was later reviewed for a sudden increase in size of the calf 4 years later. An MR scan revealed a heterogenous soft tissue mass probably of fatty origin in the posterior compartment measuring 10 × 25 cm (Figure 4A &4B) This was confirmed to be a low grade Myxoid Liposarcoma on biopsy.

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