Painful Bladder Syndrome/Interstitial Cystitis Successful Treatment with Montelukast: A Case Report and Literature Review.

Muhammad Wajih Ullah,Afshan Rehman,Sunder Sham,Wardah Siddiq,Tariq Siddiqui,Sunita Lakhani

doi:10.7759/cureus.2876

Muhammad Wajih Ullah, Afshan Rehman + Show 4 more

Open Access

https://doi.org/10.7759/cureus.2876

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Journal: Cureus	Publication Date: Jun 25, 2018
Citations: 3	License type: cc-by

Affiliation: St. Luke's Hospital

Abstract

Painful bladder syndrome/interstitial cystitis (PBS/IC) is a chronic condition characterized by pelvic pain, urinary frequency, and urgency for more than six months in the absence of urinary tract infections. The etiology of PBS/IC is still an enigma. PBS/IC is challenging for doctors to diagnose because its symptoms overlap with other diseases such as urinary tract infection, overactive bladder, or endometriosis. Hence, it is diagnosed after excluding those diseases. The prognosis of PBS/IC may vary because of multiple treatment options. In this study, we are documenting a 26-year-old female patient who was successfully treated with montelukast after diagnosed with PBS/IC.

Highlights

Painful bladder syndrome/interstitial cystitis (PBS/IC) is a disease of unknown etiology
The International Continence Society (ICS) has defined PBS as "the complaint of suprapubic pain related to bladder filling, accompanied by other symptoms such as increased daytime and nighttime frequency, in the absence of proven urinary infection or other obvious pathology." The ICS uses the term interstitial cystitis for the symptom syndrome associated with typical cystoscopic and histological features [2]
PBS/IC is a diagnosis of exclusion and careful assessment of its symptoms, physical examination, urinalysis, urine culture, pelvic ultrasound, and cystoscopy with biopsy are indicated to differentiate PBS/IC from other causes of these symptoms

Summary

Introduction

Painful bladder syndrome/interstitial cystitis (PBS/IC) is a disease of unknown etiology. Common etiologies, which could lead to an increase in urinary frequency, urgency, or nocturia, are urinary tract infection, overactive bladder, and endometriosis which were excluded and the patient was diagnosed with PBS/IC. During her stay in the hospital, she experienced shortness of breath secondary to asthma exacerbation. The following day the patient noticed a decrease in her urinary frequency and urgency She was discharged from the hospital on inhaled low dose corticosteroids and montelukast. At her follow-up visit, two months later, the patient’s urinary symptoms were significantly reduced, and the suprapubic pain was gone

Discussion

Conclusions

Disclosures