Pain syndrome therapy in patients after mammoplasty

Abstract

Purpose of the study: to study the efficacy and safety of the intravenous form of ibuprofen “Intrafen” 800 mg in patients after mammoplasty.Material and methods. The use of intravenous ibuprofen “Intrafen” 800 mg on the day of surgery for 200.0 0.9% sodium chloride solution and the next day in 27 patients of the main group after mammoplasty at the Clinic of Plastic Surgery DR. SABAZBEKOV" (Almaty, the Republic of Kazakhstan). The inclusion criterion was informed consent to mammoplasty and the absence of contraindications to the administration of Intrafen according to the instructions. The control group also consisted of 27 patients who underwent mammoplasty; as non-steroidal antiinflammatory drugs, they were prescribed a solution of ketoprofen 100 mg/day intramuscularly once.Result and discussion. The following types of plastic surgery on the mammary glands were performed: augmentation mammoplasty – 8 (29.6%), reduction mammoplasty – 10 (37.0%) and isolated mastopexy – 9 (33.4%). The intensity of pain on the VAS scale on the day of surgery was (4.5 ± 0.5) points, on the 1st day the relief was up to (1.4 ± 0.5) points. Hemodynamic parameters within 1 day were within normal limits: systolic blood pressure (113.9 ± 7.0) mm Hg, diastolic blood pressure (73.2 ± 6.47) mm Hg, heart rate (79.1 ± 4,9) beats per minute, saturation (99.6 ± 0.68) %. No gastrointestinal disturbances were found in the control group. The intensity of pain syndrome after surgery was (8.4 ± 1.3) points according to the VAS, which required the administration of an opioid solution of tramadol hydrochloride 100 mg/day and on the day of discharge the VAS was (4.1 ± 0.75) points, followed by the appointment of a solution of ketoprofen 100 mg/day once.Conclusion. The intravenous form of ibuprofen “Intrafen” 800 mg once a day of surgery and then 1600 mg/day during the day is effective for relieving pain in patients after mammoplasty and is safe due to the absence of adverse events from the gastrointestinal tract and stable hemodynamics.