Abstract
Purpose: Total knee arthroplasty (TKA) is the final treatment option for end-stage knee osteoarthritis. While it is expected to resolve pain, 15-40% of patients have persistent pain 6 months after surgery that is not otherwise explained (e.g., infection, joint loosening). While the majority of patients undergo only one knee replacement, a substantial fraction of patients has both knees replaced, and these are typically staged (performed sequentially). The implications of having two TKAs in terms of pain outcomes, and whether there is a proportion of patients who do not achieve pain resolution after two TKAs is unclear.
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