Pagetoid reticulosis Woringer–Kolopp type: A report of two cases at a third-level center

Abstract

Pagetoid reticulosis is a clinical and histological variant of mycosis fungoides that shows epidermotropism in histology and a classic clinic with acral disease. Herein, we present two clinical cases, an 84-year-old male and a nineteen-year-old male with clinical, immunophenotype, topography, and genotype compatible with mycosis fungoides-variety pagetoid reticulosis, both showing excellent responses to radiation therapy and in clinical remission. Despite the low frequency of this type of mycosis fungoides, we should keep it in mind in our differential diagnoses since, despite its benign course, it requires different treatment options and long-term follow-up. Key words: Pagetoid reticulosis, Woringer–Kolopp disease, Cutaneous T-cell lymphoma, Radiotherapy