Abstract
Paediatric Friendly Dosage Form for Enhanced Therapeutic Efficacy in Aids and the Opportunistic Infection Tuberculosis
Highlights
Acquired immuno deficiency syndrome (AIDS) is spectra of conditions caused by the human immunodeficiency virus (HIV) [1]
Each day approximately 5,000 people were newly infected with HIV and approximately 2,800 people died from AIDS, mostly because of inadequate access to HIV prevention care and treatment services in the year 2016 [2]
The paediatric buccal films prepared in the present research cater the need of preparing a patient friendly dosage form but are technologically highly superior as compared to the other commercially available
Summary
Acquired immuno deficiency syndrome (AIDS) is spectra of conditions caused by the human immunodeficiency virus (HIV) [1]. Conventional dosage forms recommended by US FDA and WHO for the treatment of AIDS involves a combination of antiretroviral drugs given in the form of tablets, capsules, oral solutions and suspension preparations. Available tablet formulation has to be broken into parts and given twice daily. Such a practice results in inconvenience to the child as well as to the person administering the medicine in addition to dose imprecision which is likely to occur leading to sub therapeutic activity of drugs or incidence of associated side effects with antiretroviral therapy which can result in failure of therapy [3,4]
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