Abstract
Abstract. The report concerns pachydermoperiostosis in two women, mother and daughter, a relationship which has never before been noted. Another unusual aspect is that the characteristic features of the condition were noted already at the birth of the daughter. Moreover both have had symptoms of disturbed gonadal function. The mother began menstruation at 20 years of age and had scanty menses. The daughter, now 30 years old, has still a primary amenorrhoea and there is a low concentration of the oestrogens and FSH excretion in the urine.
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