Abstract
BACKGROUND CONTEXT: While the use of autologous iliac crest bone graft (AICBG) has long been regarded the “gold standard” for anterior cervical discectomy and fusion; increasing numbers of surgeons are abandoning its use in favor of nonautologous materials. Bone graft donor site pain and morbidity, as well as increased operative time are factors cited by surgeons for this trend. The most commonly used substitute for AICBG is human cadaveric allogeneic bone. Freeze-dried allografts may be stored at room temperature and have an indefinite shelf life; however, the process of freeze-drying can reduce mechanical strength by 50% compared with frozen grafts. Frozen allografts maintain their mechanical strength and can be stored for up to 1 year.
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