Abstract
BACKGROUND CONTEXT: Chiari I malformations are characterized by displacement of the cerebellar tonsils more than 5 mm caudally through the foramen magnum. Typical symptoms present in these patients include headache, neck pain, sensory and motor deficits. However no direct correlation has been observed between symptoms and anatomical severity of the herniation suggesting that the pathophysiology of the disease cannot be explained by anatomical findings alone. It has been shown that a decrease in the amplitude of CSF flow velocities at the craniospinal junction is correlated with the severity of the herniation, and there is a strong coupling between the CSF flow dynamics and cerebral blood flow in these patients.
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