P91 Nitisinone treatment reduces the need for liver transplantation in children with tyrosinaemia type 1 and is associated with improved post-transplant renal tubular function

Abstract

IntroductionTyrosinaemia Type 1 (TT1) is a disorder of tyrosine metabolism which may lead to liver failure and a high risk of hepatocellular carcinoma (HCC). Treatment previously consisted of dietary restriction...