P84 RENAL DENERVATION IN RESISTANT ARTERIAL HYPERTENSION: OUR CENTER‘S EXPERIENCE

Abstract

Abstract Introduction The renal denervation procedure (RDN) represents an innovative alternative in patients with resistant arterial hypertension, in addition to medical therapy and lifestyle changes. This document presents our experience at the Cardiology department of the “Fatebenefratelli di Benevento” hospital where 19 effective RDN procedures were performed. Methods 19 RDNs were performed at the “Fatebenefratelli di Benevento” Hospital in patients with resistant arterial hypertension (defined as failure to control blood pressure values using three or more drugs, including a diuretic). The long–term efficacy of the technique was evaluated by comparing blood pressure measurements using ECG–holter before and after the RDN (follow–up visit – 12 months). In addition, patients underwent a clinical–instrumental evaluation before the procedure and at the follow–up visit. Results The analysis of the collected data revealed a significant reduction in systolic, mean (p–value <0.001) and diastolic (p–value = 0.001) blood pressure. The mean variation was –13 ± 8 for systolic blood pressure, –7 ± 7 for diastolic blood pressure, and –11 ± 9 for mean pressure. The procedure was completed in all patients without peri–procedural and post–procedural complications. During the 12 months of observation, no fatal or non–fatal cardiovascular events, hospitalization or death from any cause were reported. Conclusions In our experience, renal denervation has been a safe and efficacy procedure in reducing blood pressure and the amount of drugs taken in high–risk cardiovascular patients with resistant arterial hypertension. It will be necessary to confirm the results benefits through a longer follow up.