Abstract

The programmed death ligand-1 (PD-L1) expression is an important biomarker in the era of immunotherapy using immune checkpoint inhibitors. PD-L1 testing using the 22C3 antibody (Ab) has been the standard in determining the first-line therapy in advanced non-small cell lung cancer (NSCLC). Atezolizumab monotherapy has become a first-line treatment option based on the IMpower 110 trial result. However, there are few data on the effectiveness of PD-L1 staining using SP142 Ab.

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