Abstract
Heart transplantation is the most effective therapy for endstage heart failure of diabetes mellitus. There are very few cases who underwent heart transplantation in Japan because DM remains a relative contraindication for heart transplantation. We enrolled 45 patients in Japan Organ Transpant Network, but there was only one patient with DM. Nevertheless, the increasing prevalence of both DM and congestive heart failure makes it necessary to perform heart transplantation in near future. We performed a retrospective analysis on long-term survival in 453 patients with DM who underwent heart transplantation at Heart and Diabetes Center NRW Bochum University in Germany. Survival rate and causes of death were compared with data of a group heart transplant recipients without DM. Mean follow-up time of all heart transplant recipients was 68.2 months (range: 0 204 months). Overall mortality during follow-up was 42.9%. Long-term survival did not differ significantly between study groups (P= 0.32). In addition, there was no significant differences in survival rates between groups with advanced DM and without DM. Steroid-free immunosuppressive therapy was associated with a higher percentage of long-term survivors compared with no steroid-free immunosuppression. Our data demonstrate that long-term survival is acceptable in heart transplant recipients with preoperatively diagnosed DM.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
