Abstract

Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly being used over warfarin for stroke prevention in non-valvular atrial fibrillation (NVAF) patients. However, there are limited studies on clinical outcomes of NOAC in a multi-ethnic Asian country such as Singapore. This study aims to compare the real-world effectiveness and safety between NOAC and warfarin in NVAF patients and assess the potential long-term impact on the healthcare system in Singapore.

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