Abstract
Pulmonary carcinoids are well-differentiated neuroendocrine neoplasms with a general indolent behaviour. However, some patients with carcinoid develop recurrence of disease after curative surgery. Previously, loss of Orthopedia Homeobox (OTP) RNA and protein expression has been independently associated with a poor prognosis independent of histological subtype. The regulatory mechanism underlying OTP expression, however, remains to be elucidated. Here, we investigated OTP expression in 37 different cancer types and unmasked the mechanism regulating OTP expression in lung neuroendocrine neoplasms (LNENs).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
