Abstract
There is currently potential overuse of adjuvant chemotherapy (AC) in patients with stage II colon cancer (CC) given the uncertain survival benefit in unselected patients. A circulating tumour DNA (ctDNA) approach has the ability to improve patient selection for AC, defining patients who may benefit from treatment (ctDNA positive) and those who will not (ctDNA negative). This study aimed to estimate the health and economic impact of ctDNA-guided prescription of AC for stage II CC.
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