P61.02 The Use of PLCOm2012 vs PLCOm2012noRace Risk Prediction Models in a UK Lung Cancer Screening Programme

Abstract

The PLCOm2012 lung cancer (LC) risk prediction model can be used to select participants most likely to benefit from low-dose CT (LDCT) screening. It was derived and validated in a North American population, including categories such as American Native & Native Hawaiian. Therefore a re-parametrised version of the model, PLCOm2012noRace, which removes the ethnicity predictor, has been suggested as more globally applicable. We sought to evaluate the clinical impact of switching between these two models in a UK screening programme.