Abstract

Comprehensive molecular testing is essential to provide personalized and effective care for patients with metastatic non-squamous (non-Sq) NSCLC. Ordering of next-generation gene sequencing (NGS) is often delayed until the first medical oncology visit. To improve rates of timely comprehensive molecular profiling among newly diagnosed patients with advanced non-Sq NSCLC, we implemented a reflex, molecular testing pathway (NGS and RNA fusion panel) on tumor, nodal or metastatic specimens, initiated at the time of initial pathology review, that obviated the need for a separate specimen-specific order.

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