Abstract
Recently, involvement of immune cells such as T cells, activation of immune effector cells, and reduction of immunosuppressive cells have been shown to be a part of mechanisms of antitumor effect of chemotherapy. Some chemotherapy and radiotherapy induce immunogenic cell death (ICD), leading to immune response against cancer cells. However, the expression of ICD related factors in clinical specimens are still unknown. We investigated the expression of ICD related factors before and after chemoradiotherapy in non-small cell lung cancer (NSCLC) and analyzed its relationships with other clinicopathological characteristics of lung cancer.
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