Abstract
Waste clearance in the brain is mediated through the glymphatic system, which has been explored in neurodegeneration, sleep, and aging. Genetic, metabolic-vascular, and neuroimaging evidence suggest that clearance of debris via the glymphatic system is affected in schizophrenia (SCZ). We aimed to quantify the aggregation of high-molecular-weight macromolecules (MM), as a measure of compromised glymphatic system, in patients with SCZ. We hypothesised: 1) patients with SCZ would have higher MM levels than controls; 2) Age would be associated with less glymphatic system efficiency in both SCZ and controls.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
