Abstract

Abstract Background The clinical impact of prior percutaneous coronary intervention (PCI) in patients requiring surgical revascularization (CABG) is not well investigated. We explore whether prior PCI is associated with adverse outcome after CABG. Methods and Results Operations conducted between October 2014 and July 2021 at Magna Graecia University were analyzed using propensity weighted methodology to adjust for confounding. Of a total of 1410 adult patients included in the study, (24%) patients had a history of PCI. At multivariable level, prior PCI was not associated with an increased hospital mortality in both unweighted and weighted patient groups (odds ratio, 0.77; 95%; P = 0.41 and odds ratio, 0.93; 95% confidence interval; P = 0.84, respectively). Subgroup analyses confirmed that prior PCI had no impact on hospital mortality and morbidity, including reexploration for bleeding, blood transfusion, hospital resource use, and neurological, renal, and cardiac complications. Conclusions Our study showed that prior PCI was not associated with an increased risk of mortality or other adverse outcomes in patients undergoing CABG. Further studies are needed to ascertain the prognostic impact of prior PCI in the outcome after CABG.

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