Abstract
In certain cases of complex sleep disordered breathing (SDB), central and obstructive patterns may shift or overlap. Central SDB (CSDB) is typically unresponsive to continuous positive airway pressure (CPAP). Atrial overdrive pacing (AOP) may have an effect on central but not obstructive SDB (OSDB). We report two cases of SDB in which AOP substantially reduces CSDB while increasing OSDB. This effect of AOP may help provide insight into underlying mechanisms of complex SDB.
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