P-430: Impact of body mass on pregnancy rates in women undergoing intrauterine insemination

Abstract

To determine the clinical effect of body mass index (BMI) on pregnancy rates (PR) in women undergoing intrauterine insemination (IUI). A prospective analysis of 1465 IUI cycles to determine the effect of BMI on PR. Women undergoing medicated and unmedicated IUI cycles from January 2004 to April 2006 were analyzed prospectively for clinical pregnancy. Clinical pregnancy was defined as the presence of an intrauterine sac documented by ultrasound. Patients were grouped according to BMI: <18.5, 18.5-24.9, 25-29.9, >35. Differences in PR between the BMI groups were determined statistically by Chi Square analysis. p<0.05 was considered statistically significant. Significant differences in PR based on BMI were not seen in women undergoing IUI cycles except in the obese group (30-34.9 kg/m2) vs. the morbidly obese (>35 kg/m2), p<0.05. Tabled 1 Significant differences in PR were not observed for women in the different BMI groups. However, there was a statistically significant difference between the obese vs. morbidly obese patients which may potentially be related to fertility diagnosis. The morbidly obese group seems to have a higher incidence of anovulation. Therefore, this patient population may be more easily treated with medicated IUI in comparison to the other groups which have a more varied diagnosis.