P425. Trauma Affects the Oscillatory Dynamics Serving Verbal Working Memory in Sex- and Developmentally-Specific Ways

Abstract

Working memory, the ability to hold items in memory stores for further manipulation, is a higher-order cognitive process that supports many aspects of daily life. Childhood trauma has been associated with altered cognitive development including particular deficits in verbal working memory, but the neural underpinnings of this deficit remain poorly understood. Magnetoencephalography studies of verbal working memory have reliably shown decreased alpha activity in left-lateralized language regions during encoding and increased alpha activity in parieto-occipital cortices during the maintenance phase.