Abstract

The aim of our study was to evaluate the impact of medical clowning following embryo transfer on pregnancy rates after IVF-ET. Medical clowning involves a new approach of using humor as an adjunctive therapy in medical situations. No reports are available concerning the impact of humor on infertility or the outcome of IVF. A prospective randomized study was performed in a university affiliated IVF unit. A medical clowning session of 10-15 minutes was especially composed, suitable for couples under fertility treatment. The medical clown team of our center invented this program. 186 patients who underwent IVF-ET at the IVF unit of Assaf-Harofeh Medical Center were included in the study. Following routine embryo-transfer procedure, every other Thursday for a period of 10 months, all patients were offered a personal encounter with a professional medical clown who performed a similar bedside routine session. Bits of this medical clown session will be shown by a short video. The outcome of the treatment cycles of patients who had an encounter with the medical clown (study group) was compared to the outcome of the patients, who had a routine embryo transfer on a successive Thursday, who did not encounter a medical clown (control group). 186 patients were included in the study and control groups. Patients mean age (34.0±5.0 vs 33.9±6.1, p=ns, study and control groups respectively), length of infertility (3.9±3.0 vs 4.1±3.1 years, p=ns, study and control groups respectively), number of previous IVF cycles (3.1±3.6 vs 3.0±3.2, p=ns, study and control groups respectively), indications for IVF between the two groups were comparable. Regarding the treatment cycle parameters, the number of oocytes retrieved were comparable (11.2±8.1 vs 11.2±7.2, for the study vs control groups, p=ns). Although the mean number of embryos transferred was less in the study group (2.3±0.8 vs 2.6±1.4, p<0.01), 33 patients out of the 93 in the study group conceived (35.5% per embryo transfer), whereas only 18 patients out of the 93 in the control group conceived (19.3% per embryo transfer). This difference was significant (p=0.002, Chi-square test), Odds ratio 2.29; 95% CI limits: 1.11-4.72. For the first time, in a prospective randomized study, medical clowning has been shown as an original, effective adjunctive intervention having a beneficial effect upon outcome of IVF-ET. The benefits of use of humor and medical clowning should be further investigated in conjunction with infertility and its treatment.

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