Abstract
Dystrophia Myotonica type 1 (DM1) is the most common muscular dystrophy. Aerobic exercise improves fitness in DM1 patients. Whether the improvement is caused by improved cardio-respiratory fitness or increased muscle net-protein synthesis is not known. In healthy individuals exercise, especially in combination with protein-intake improved muscle protein anabolic state. Therefore, we investigated how exercise combined with protein-supplement affected skeletal muscle metabolism in DM1 patients. Seven DM1 patients and 6 healthy controls were studied during two trials with and without oral protein-supplementation for 3h in the recovery phase from exercise.
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