P388 OUT OF HOSPITAL CARDIAC ARREST ( OHCA) OUTCOME : ARE THERE GENDER DIFFERENCE ?

Abstract

Abstract Background Sudden cardiac death ( SCD) from cardiac arrest ( SCA) represents 25% out of all deaths. Despite the advance in resuscitation and prevention of SCA, out of hospital arrest ( OHCA) accounts only a 10 % of survival . Coronary artery disease is the major underlying etiology . Females have lower incidence of SCD. However data regarding OHCA outcome in female are controversial. Methods We considered consecutively 3124 OHCA survivors resuscitated from emergency medical System or bystander In Piacenza between from January 2013 to June 2022 and we e evaluated the etiology and outcome, considering sex and gender disparities. Results Out of 3124 SCA occured in 10 years, 1371(43%) were females with average age 82 ±12 years and 1753 ( 57%) males with average age 75 ±14 years ( p<0,0001) . The survival of our population was 10% with better results in males ( f 3,1% vs 14% m p<0,0001) 1268 females and 1482 males were treated at home. 2366 ( 75%) patients,1091 ( 46%) female and 1275 ( 54%) males,developed an initial non shockable rhythm and 323( 25%), 242 (74%) females and 81 (26%) males ventricolar fibrillation ( FV) . In the group with FV as initial rhythm, the survival was 40% . Considering etiology in the group with FV as initial rhythm, females had less incidence of coronary artery disease ( 5 f vs 48 m, p=0,004) and myocardial infarction (f 1 vs 33 m, p=0, 001). The survival wasn’t different between females and males in this group.( 22 f vs 64 m, p=0,8). Female had more frequently non shockable rhythm ( 79 % f vs 72 % m, p< 0,001) and were found more frequently at home ( 92% vs 85% p < 0,001). Conclusions In our OHCA population, the survival was 10% in according with literature Female were older and they had less survival, because initial rhythm registered during SCA were non shockable rhythms. They were found at home,with a delay in the first aid . This can be due to a gender disparities.