P37-F Predictors of cognitive impairment in patients with mine blast injury

Abstract

Background Mine blast injury is accompanied by traumatic brain injury (TBI) in 60–100% of cases. TBI is associated with cognitive impairment (CI). However, predictors of CI in this patients (pts) are studied insufficiently. Material and methods 115 men aged 18 to 45 years with mild TBI caused by using of mine-blasting weapons. Cognitive functions were evaluated by using MoCA test, HADS scale. Cognitive dysfunction was defined as MoCa ⩽ 25 scores. Besides routine examination, neurophysiological methods such as quantitative electroencephalography (qEEG) and cognitive evoked potentials P300 (CEP P300), were performed. Results. In binary logistic regression predictors CI were complaints on headache and fatigability (OR 2.52, 95% CI 2.6–59.7, p = 0.02), increased tendon reflexes (OR, 2.6, 95% CI 1.24–2.32, p = 0.017), higher HADS anxiety level (OR-1.8, 95% CI 1.59–2.2, p = 0.04), changes of alpha rhythm frequency (OR-1.02, 95% CI 1.01–1.04, p = 0.004), decrease of alpha rhythm amplitudes (OR - 1.07, 95% CI 1.03–1.11, p Conclusions changes in qEEG and CEP P300 parameters are reliable independent predictors of CI in pts with TBI affected by mine blast trauma.