P359 Quality of life in ulcerative colitis patients treated medically versus patients undergoing surgery

Abstract

OBJECTIVES: Approximately one third of patients with ulcerative colitis (UC) re - quire surgery. AIM: Aim of this study was to assess the quality of life (QoL) of UC patients who have un - dergone surgery with ileorectal anastomosis (IRA) or ileal pouch-anal anastomosis (IPAA) compared to UC patients not operated. PATIENTS AND METHODS: Fifty consecutive UC patients for each group observed between 1988-2010 were included. To all patients was ad - ministered a self completed questionnaire with four different scores: intestinal symptoms (IS), systemic symptoms (SS), emotional function (EF), social function (SF) and an overall QoL score. RESULTS: Overall QoL score and three dimen - sions (SS, EF, SF) resulted not significantly dif - ferent in the three groups, except for IS that re - sulted worst in the IRA-Group. According to the activity of disease it appeared that UC and IRA patients with mild activity had an overall QoL score similar to patients with complicated IPAA. A higher statistically different score of overall QoL was observed in patients with UC and IRA with moderate/severe disease. CONCLUSIONS: Results of the study demon - strate that overall QoL score is poorer in patients with UC and IRA with mild activity and in patients with complicated IPAA and is worst in patients with UC and IRA with moderate/severe activity .