P-346 Endoscopic profiling of various GI malignancies in CMOSH Medical College Hospital, Chattogram, Bangladesh

Abstract

The prevalence of GI malignancies in Chattogram, Bangladesh, is mostly unknown. We, gastroenterologists, often find various GI malignancies during gastro-duodenoscopy, colonoscopy and ERCP. However, we have no DATA regarding the epidemiology of these malignancies which are diagnosed endoscopically. We did this study to profile various GI malignancies diagnosed endoscopically at our centre. Moreover, we audited the endoscopy reports with diagnosis of GI cancer to improve the quality of our performance and reporting. Endoscopy reports of 93 consecutive patients presenting to the endoscopy suits of CMOSH from May 2017 until April 2019 and diagnosed as GI malignancies were retrospectively analyzed. The DATA regarding various procedures performed, age, and gender were recorded from the endoscopy reports. DATA on carcinoma of oral cavity, oesophagus, stomach, duodenum, ampullary, peri-ampullary region, bile duct, colon and rectum were analyzed using STATA software; version 13 (StataCorp, College Station, TX). Total number of subjects: 93; male 56 and female 37. Site of cancer: We found cancers in the oral cavity 3 (3.23%), oesophagus 22 (23.66%), stomach 31 (33.33%), Duodenum 3(3.23%), ampullary and periampullary 20 (21.51%), biliary 1 (1.08%), and rectum and colon 13 (13.98%). Among 22 oesophageal cancers the majority 18 (81.82%) involved lower oesophagus, 2 (9.09%) involved middle oesophagus. 2 (9.09%) involved upper oesophagus. Among 31 carcinoma stomach cases majority 17 (54.84%) involved antrum, 7(22.58%) involved body, 3 (9.68%) cardia, 2 (6.45%) fundus and 2(6.45%) pylorus. Among 13 colorectal cancers, 6 (46.15%) involved rectum, 4 (30.77%) sigmoid colon, 1 (7.69%) each in ascending, descending and transverse colon. Age group distribution of GI cancers: Age group distribution of our subjects was: 20 and below: 1 (1%), 21-30: 6 (6.45%), 31-40: 10 (10.75%), 41-50: 17 (18.28%), 51-60: 22 (23.66%), 61-70: 25 (26.88%), 71-80: 6 (6.45%), 81-90: 4 (4.30%) and 91 and above: 2 (2.15%). The subjects belonging to the 61-70 years age group had the most GI cancers in our study. Prevalence of cancer in this age group was: oral cavity 2, oesophagus 8, stomach 9, Duodenum 5 and rectum 1. Second age group was 51-60 years. Cancers found in this age group was: oesophagus 5, stomach 5, duodenum 9, rectum 1 and colon 2. Third age group was 41 to 50 years. Cancers which were prevalent in this age group were: oesophagus 2, stomach 5, duodenum 6, biliary 1, rectum 1 and colon 2. Gender distribution of GI cancers: Commonest cancer in female subjects was oesophagus 12, which was followed by stomach 8, colorectal 8, ampullary/preiampullary 4, duodenum 3 and biliary 1. Most common cancer in male subjects was gastric cancer 23, which was followed by ampullary/periampullary 16, oesophagus 10 and colorectal 5. Our subjects were predominantly male belonging to age group 61-70 and predominant cancer in our study was gastric cancer. The most common cancer in female subjects was carcinoma oesophagus and the most common cancer in our male subjects was carcinoma stomach. Although there were some minor differences in the reporting and occasional omission of details, we found the reporting quality as optimum.