P320. Waiting for the Payoff: Electrical Anticipation Response in Individuals With Depression/Anxiety Disorders

Abstract

Reward processing dysfunction is considered a core characteristic of depression and anxiety disorder (DEP/ANX). However, research in DEP/ANX has focused mainly on reward receipt as opposed to anticipation. The stimulus preceding negativity (SPN) is a slow event-related potential recorded during electroencephalography (EEG), thought to reflect anticipatory brain activity. We aimed to examine the effect of MDD on SPN amplitude and its relationship with future treatment completion (>7 sessions of behavioral activation or exposure therapy).