Abstract
Background Malignant pleural mesothelioma (MPM) is an aggressive malignancy related to asbestos exposure. Trimodality therapy (TMT) involving extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D) with neoadjuvant or adjuvant chemotherapy and adjuvant radiotherapy is a widely accepted treatment protocol with curative intent. Recently a combination of TMT with intracavitary treatment strategies has been reported to be beneficial. In this study we investigated the impact of TMT in combination with intraoperative hydrogen peroxide treatment in patients with MPM.
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