Abstract
ABSTRACT Tumors of histiocytes are among the rarest of tumor affecting lymphoid tissues. As these tumor types were poorly recognized until recently, it is sometimes difficult to establish diagnosis and their clinicopathological features are still obscure. Here, we report a case of hitiocytic/dendritic neoplasm with marked blood coagulation disorder. A 71-year-old woman was admitted to the hospital for progressive abdominal distention and bilateral cervical lymphadenopathy lasting for a month. Computed tomography scan showed marked hepatosplenomegary and ascites and low gastrointestinal endoscopy showed ileal neoplasm. Pathological findings of the tumor showed proliferation of large pleomorphic cells with abundant and eosinophilic cytoplasm and infiltration with small T-lymphocytes. She was suspected with malignant lymphoma and transferred to our hospital after one week from her first hospitalization. On admission, her performance status was 3 and she showed systemic subcutaneous bleeding and marked abdominal distention. Her laboratory data showed marked blood coagulation disorder (Plt 2.6 × 103/m3, PT INR 1.74, APTT 51.1 s, Fib 60 mg/dl, AT III 14%, FDP-s 2.8 mg/ml, PIC
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