Abstract

The cobas® EGFR Mutation Test v2 (Roche Molecular Systems Inc.) has recently been IVD approved in the US for detection of epidermal growth factor receptor (EGFR) mutations in blood samples. Knowledge of the EGFR mutation status in non-small cell lung cancer (NSCLC) patients is essential to designing optimal, individualized treatment. However, implementing blood-based analyzes to detect cancer-specific mutations demands standardized pre analytical conditions, but research in this field is rare and inadequate.

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